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It also highlights the importance of taking supplements in moderation rather than in excessive amounts

And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon

[13] [15] There is a risk of oxalate nephropathy or kidney stone formation, particularly in patients with pre-existing renal impairment or those receiving prolonged high-dose therapy

Anjan Chatterjee told me that there just arent enough studies of these drugs in normal people. He said, In the situations where they do help, do they come with a cost? As he wrote in a recent letter to Nature , Most seasoned physicians have had the sobering experience of prescribing medications that, despite good intentions, caused bad outcomes. Given that cognitive enhancement is a choice, not a necessity, the cost-benefit calculation for neuroenhancers should probably be different than it is for, say, heart medications